The church of San Miniato al Monte was originally begun in 1018 on the site of a 4th century chapel. The adjoining bishop's palace was built in 1295-1320 while the unfinished bell tower is from the 15th century.
The baptistery of St John was built between 1059 and 1128 as the third baptistery on the site. The first was constructed in the late fourth century or early fifth century. The marble supposedly came from Fiesole, which was conquered by Florence in 1078, while the rest came from ancient structures. The lantern was added in 1150, while the entrance porch is from 1202.
Orsanmichele was originally built as a grain market in 1337 by Francesco Talenti, Neri di Fioravante and Benci di Cione. It was converted into a church for the craft and trade guilds in 1380-1404. The statues are copies of the originals, which were commissioned by the guilds in the early 15th century.
The design of Palazzo Rucellai has been attributed to Leon Battista Alberti and dated to 1546-51, though this is still subject to debate. Actual construction was probably piecemeal and not completed until 1460s when the Rucellai family succeeded in buying the neighbouring properties. In fact, the facade should have been one bay wider than what was built and lacks symmetry as a result. A very similar design is used on Palazzo Piccolomini in Pienza by Bernardo Rosselini, which could be the architect for both palaces. It is seen as the first consistent attempt to apply classical orders to palace front, an inspiration which probably came from the Colosseum. The use of a richer Corinthian order on the first floor doesn't match the classical model but is consistent with the contemporary idea of a piano nobile being the most important part of the building.
San Frediano in Cestello was built in 1680-89 to a design by Gherardo Silvani. The dome was added in 1689 by Antonio Maria Ferri. It replaced a previous church from the 1450s.